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Anaphylactiod syndrome of pregnancy, DIC, recombinant factor VIIa
CASES: Case 1 details a 36-year-old woman at 39 weeks and 2 days gestation that developed seizures, hypotension and bradycardia with noted fetal distress following an augmentation of labor. Case 2 describes a 30 year-old woman who presented for a scheduled induction of labor at 39 weeks and 1 day gestation and experienced sudden onset of severe back pain, shortness of breath, and tachycardia. Both women developed disseminated intravascular coagulapathy (DIC), which was successfully managed with recombinant factor VIIa.
CONCLUSION: Recombinant factor VIIa treatment has some risks, but is cases such as the two women presented in this report, its use can be lifesaving.