T cell Non-Hodgkins lymphoma as a cause of Hypercalcemia: an important differential to remember

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RAGHUNATH PRABHU
Neha Kumar
Sakshi Sadhu
Rajgopal Shenoy

Keywords

Hypercalcemia, Non-Hodgkins lymphoma, T cell

Abstract

Malignancy often manifests itself as hypercalcaemia, an electrolyte abnormality that can lead to several other systemic consequences. In T cell non-hodgkins lymphoma, more than half the patients (about 60%) present with symptoms of hypercalcaemia. It is rare in B cell non-hodgkins lymphoma (B-NHL), with only 5-8% of cases manifesting with hypercalcaemia1. Peripheral T cell lymphomas make up a very small percentage of lymphomas. We present a case of a 46 year old male who initially presented with diffuse abdominal pain and hypercalcemia. He was evaluated for sarcoidosis. Further imaging and a biopsy revealed T-NHL with hypercalcaemia